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Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

A study further revealed that the exonuclease MYG1 promotes tumor adaptation and progression in CRC by coordinating nuclearmitochondrial signaling, thereby boosting both glycolysis and mitochondrial function [68]

For instance, co-administration of curcumin with 5-FU or cisplatin has been shown to significantly improve the cytotoxic effects of these drugs on GC cells, leading to increased cell death and reduced tumor growth compared to chemotherapy alone

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density

Evidence for prolonged release of excitatory amino acids in severe human head trauma