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Description

Found in the pituitary gland in vertebrates including humans, -MSH is a melanocortin receptor agonist that contributes to several physiological processes, including melanogenesis, appetite modulation, and sexual desire

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After ADC internalization via receptor-mediated endocytosis, the conjugates are transported to acidic organelles such as endosomes and lysosomes, where pH values typically range from 4.5 to 6.0

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Its dysregulation has been implicated in a wide range of diseases, including cancer, neurodegenerative disorders, metabolic syndromes, muscular diseases, and infections

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