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Inhibition of the CD40-TRAF6 axis thus holds substantial promise for mitigating the inflammatory response

Peptides are chemically sensitive materials, and reconstitution behaviour can be influenced by the exact diluent used

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In an ongoing phase 1a/1b trial of leptomeningeal metastases (malignant cells in the CSF), IT DFO will be tested through an Ommaya reservoir to determine the highest dose of DFO that can be tolerated (Clinicaltrials.gov, 2025), but full results are still pending

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