l-carnitine male hormone L. carnitine modulates oxidative stress, steroidogenic gene disturbance, and testicular histopathology induced by Bisphenol A in rats | Veterinary Research Communications L-Carnitine supplementation

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Relationship between abnormal expression of PI3K/AKT pathway-related protein and insulin resistance of rats of polycystic ovary syndrome with endometrial insulin resistance

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Liu Y, Bell T, Zhang H, Sun Y, Li CJ, Feng N, Huang S, Guo H, Wang J, Ahmed M, Zhang V, Lam LT, Nomie K, Zhang L, Di Francesco ME, Marszalek J, Wang M

It mediates the deacetylation of nicotinamide nucleotide transhydrogenase (NNT) by activating Sirtuin 1 (SIRT1), enhances the catalytic activity of NNT to increase NAD + levels, and forms a SIRT1/NNT/NAD + positive feedback loop, thereby maintaining mitochondrial metabolic homeostasis