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2.3.1 Cognitive impairment METH abuse significantly impairs cognitive function by targeting key brain regions (McCann et al., 2008), such as the hippocampus, striatum, amygdala, and prefrontal cortex
PMC 2910991
GLP-1 is secreted, among others, from the brains preproglucagon neurons in the nucleus tractus solitarii and works within the paraventricular nucleus and the arcuate nucleus, causing satiety [64]
However, research suggests that PD may also be a manifestation of systemic conditions, particularly those involving fibrosis, vascular dysfunction, and metabolic disorders
