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39 13.2 The Second Wave: Government v

As the demand of cigarettes has increased so has the supply

Side effects can include: Anxiety Changes in appetite Changes in mood Diarrhea Dizziness Drowsiness Dry mouth Increased tremor in certain groups Inhibition of hepatic drug metabolism/decreased activities of p-glycoprotein and other drug transporters Light headedness Low blood pressure Nausea Vomiting A contraindication to be aware of when taking CBD is its effect on the group of liver enzymes called cytrochrome P450 enzymes

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Surgery If sciatica symptoms do not improve after 6-8 weeks of nonsurgical care, microdiscectomy or other spine surgery may be warranted