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Treatment works by targeting this process at two levels: Acute relief medications (NSAIDs, colchicine, corticosteroids) act directly on the inflammation, reducing pain and joint swelling within hours to days

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In the future, ongoing medicinal chemistry campaigns, i.e., small molecules that target PDH beyond DCA (VER246608, anilide tertiary carbinols, and others) should be leveraged in combination with established animal models of cyanide poisoning

These results support previous findings which indicate that NAC possess mycobactericidal capacity (1CE)