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Click for Answer The table below presents a differential diagnosis of macrocytosis with findings in our patient that support or do not support one or another diagnosis: What is the next lab test you would order

Although this is consistent and mechanistically validated across different preclinical models, as reviewed in the Preclinical and clinical applications of NAD + -modulating interventions for mitochondrial homeostasis and health benefits section, the correspondence between NAD + changes and mitochondrial or metabolic alterations is more complex in human studies