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Experientia 1982

Conflict of interest The authors declared that the manuscript was written in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Moreover, Mn-deficient diets exacerbate colitis in mice, whereas Mn supplementation restores epithelial integrity and reduces mucosal injury (Choi et al., 2020)

Ethics declarations Ethics approval and consent to participate The Ethics Committee of The Third Hospital of Qinhuangdao approved all experimental protocols