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B 11 (9), 29372944

10.3390/ijms17081328 169

The results of the Phase III studies only provide evidence for treating individuals within 12 months of symptom onset

However, forced overexpression of PRDX5 significantly protects tendon cells, reducing H 2 O 2 -induced apoptosis by nearly half and preventing the decline in collagen synthesis (Yuan et al., 2004)