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Tayran H, Yilmaz E, Bhattarai P et al (2024b) ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimers disease through BDNF/NGFR signaling

This small molecule, with its unique molecular structure, has been linked to potential interactions with amino acids and as a potent activator of sirtuins, a class of proteins involved in regulating cellular health and longevity, suggesting a nuanced role in cellular processes that may further contribute to the compounds anti-aging properties

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Conclusion We found that the use of metformin at doses equal to or greater than 1500 mg/d is a major factor related to the development of vitamin B12 deciency, and that concurrent supplementation of multivitamins may potentially protect against this