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[DOI] [PMC free article] [PubMed] [Google Scholar] 360

PMID: 36561385

J Pharmacol Exp Ther 303:96978 Le HT, Franklin MR (1997) Selective induction of phase II drug metabolizing enzyme activities by quinolines and isoquinolines

It is a regulated cell death pathway characterized by the accumulation of lethal lipid hydroperoxides resulting from tissue iron reacting with esterified polyunsaturated fatty acids (PUFAs), especially n-6 PUFAs such as arachidonic acid [22, 23], while n-3 fatty acids [24], and n-9 monounsaturated fatty acids [25] are protective