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Their prior work revealed that Bacteroides vulgatus can also induce PCOS-like phenotypes by down-regulating GDCA and TUDCA levels through the BSH pathway, which inhibits IL-22 secretion by ILC3s ( speA -dependent agmatine pathway, identified in the current study, represents an additional significant mechanism by which Bacteroides vulgatus contributes to PCOS, operating independently of BAs

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However, the causal relationship between high apoC1 levels and diabetes is questionable

Additionally, some studies have evaluated outcomes over 12 weeks or longer, though individual responses may vary

Verwer MC, Waissi F, Mekke JM, Dekker M, Stroes ESG, de Borst GJ, et al