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Mitochondrial disorders in humans are genetically transmitted and caused by abnormal mitochondrial DNA, affecting nearly every medical condition [23]

Moreover, prophylactic treatment with either sildenafil or tadalafil improved cardiac contractile function and survival by attenuating doxorubicin-induced apoptosis and cardiac oxidative stress without interfering with the antitumor efficacy of doxorubicin in both in vitro and in vivo tumor models [161,162]

TABLE 1 Application of bacterial delivery of anticancer drugs in cancer treatment

If typical symptoms recur earlier, we recommend an earlier check-up

J Neurochem 67:13751382 Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent