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After the substrates are released into the matrix, mitochondrial aspartate binds to the mstate and triggers conformational changes, shifting the protein to the cstate via an occluded state

However, as with any intervention, its important to weigh the benefits against potential side effects, which can vary depending on the individual

Lackovic J, Jeevakumar V, Burton M et al (2023) Peroxynitrite contributes to behavioral responses, increased trigeminal excitability, and changes in mitochondrial function in a preclinical model of migraine

Zhang X, Li X, Wang Y, Chen Y, Hu Y, Guo C et al (2022) Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis