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10.1007/s10753-019-01060-8 Inflammation 82 ZhangY.LiZ.KholodkevichS.SharovA.FengY.RenN.et al (2019)

4144 This activation enhances the activity of POMC neurons, which induce satiety, while suppressing NPY neurons that drive hunger

For example, a major driver of white matter demise is excitotoxicity, a consequence of the excessive glutamate released by vesicular and nonvesicular mechanisms from axons and glial cells