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The oxidative stress generating anti-cancer compound RITA reduces TrxR1 activity in cell cultures by altering the oligomerization status of TrxR1 and increasing levels of inactive and cross-linked dimers (Xu et al., 2015)

Cheng Z, Yang Q, He H, Li R, Li X, Jiang H, Zhao X, Li J, Wang L, Zhou S, Zhang S (2022) Intravoxel incoherent motion diffusion-weighted imaging and shear wave elastography for evaluating peritumoral liver fibrosis after transarterial chemoembolization in a VX2 rabbit liver tumor model

He determined that to treat illness, one had to address patients emotional and mental states, and following the principles of homeopathy, he devised the flower essences for that purpose