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When the gut lining is exposed to severe irritantssuch as bacterial endotoxins (LPS) or excessive ammonia produced by dysbiotic bacteriathe epithelial cells release zonulin, which signals the tight junctions to open, increasing intestinal permeability

Huang, Y., Ren, J

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Open Joint Surgery (Arthrotomy) requires a larger incision to access the TMJ directly

In laboratory settings, it has demonstrated a remarkable ability to promote healing in a variety of tissues, from muscle and tendon to gut and even nerve tissue