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Epigenetic regulation plays a role in the adaptive responses of ACL fibroblasts to mechanical loading

In the rat acute lung injury model, Tanshinone IIA inhibited inflammation and oxidative stress, reduced glycocalyx degradation, and improved lung function [124]

(2016) 137:e20153684

Nonetheless, targeting the FABP5GPX4 axis could represent a novel adjunct strategy to potentiate current biologics, reduce required dosages, and mitigate side effects