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Although the main ingredient in most e-cigarettes is nicotine, many other compounds are included, some of which may have addictive properties or be actively harmful

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For example, California's flavor ban on e-cigarettes has affected product availability, shaping consumer behavior and market trends

There was heterogeneity in the reported RRs across studies, but our meta-analytic method fit the data and covered the estimated residuals (Extended Data Fig

Listen to this episode of Inside the FBI for an in-depth look at LEOKA data collection