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There are 7,000 chemicals in tobacco smoke, of which 250 are known to be harmful (including hydrogen cyanide, carbon monoxide, and ammonia) and 69 can cause cancer

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Prolonged exposure to nicotine leads to changes in the brains structure and function, specifically in areas responsible for decision-making, impulse control, and emotional regulation

Needham, Mass., enacted the first law restricting tobacco purchases to those 21 and up roughly two decades ago

Over time, the brain becomes less sensitive to dopamine, requiring more nicotine to achieve the same effects, a process known as tolerance