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Furthermore, misaligned chromosomes and micronuclei were also detected in human 293FT cells depleted of MED4, and the frequency of these mitotic defects was significantly increased in MED4-depleted cells compared to controls (Supplementary Fig

The second term is the activation of CBS by SAM and SAH that was discovered by Finkelstein and Martin [22]

The ability to tailor drug formulations to individual patient needs and fabricate complex structures with precise control over the size, shape, and composition has revolutionized drug development and personalized medicine [232,233]

Environmental toxins such as rotenone and paraquat, which cross the bloodbrain barrier, impair electron transport chain function and increase ROS production (262)