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The locus ceruleus innervates many cell types that are affected in ALS, so ALS could result from toxicant-induced interactions between the locus ceruleus and motor neurons (18)

To enable selective and efficient cell type-specific drug delivery in the brain, we need to understand its cellular and molecular landscape in health and disease

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Subsequently, GSH ester (100 M) was added to replenish the intracellular GSH loss, which led to recovery of GSH to the basal level in the next 3 min, as recorded by RT (Fig