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There are several studies reporting considerable variations in the hepatic ontogenic gene expression pattern of the major CYPs in children and the elderly

Based on their physicochemical properties, OSCs can be categorized into two primary groups: lipophilic (fat-soluble) and hydrophilic (water-soluble) compounds, as shown in Figure 2

J Am Chem Soc 131 (36): 1290812909

PMID: 33417003 Azzeh FS, Kamfar WW, Ghaith MM, Alsafi RT, Shamlan G, Ghabashi MA, Farrash WF, Alyamani RA, Alazzeh AY, Alkholy SO, Bakr EH, Qadhi AH, Arbaeen AF (2024) Unlocking the health benefits of melatonin supplementation: A promising preventative and therapeutic strategy