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10.1016/j.numecd.2023.10.013 Nutr Metab Cardiovasc Dis

The two peptides target different receptor systems, which is the primary rationale for studying them in combination

In Arabidopsis, only the plastidial GR2 is essential ( S -nitrosylated in a catalase mutant ( noe1 ) which displays elevated level of H 2 O 2 that promotes NO production ( in vitro by GSNO, but it did not impact their activity (Rouhier et al., 2005)