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Similarly, nucleic acid-based aptamers have gained attention because of their high affinity, low immunogenicity, and ease of chemical synthesis, allowing them to function as antibody-like targeting agents in nanoparticle systems ( Recent developments have further integrated multifunctional targeting mechanisms into next-generation nanocarriers to overcome biological barriers associated with tumor heterogeneity and the complex tumor microenvironment

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Subcutaneous injections like semaglutide occasionally trigger localized itching, redness, or mild swelling at the injection site

Matrix Biol (2013) 32:1422