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doi: 10.1016/j.cmet.2022.08.002 89 Reina-CamposMScharpingNEGoldrathAW

By inhibiting epigenetic enzymes like DNMTs, compounds such as curcumin and apigenin reduce CpG hypermethylation in the NRF2 promoter, leading to elevated NRF2 levels and offering potential therapeutic benefits for diseases associated with oxidative stress [35, 149]

These quantitative boundaries are essential for achieving consistent AgNP morphology and have been incorporated into this revised review to enhance methodological rigor and reproducibility (Balamurugan et al., 2024