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The study was supported by the Deutsche Forschungsgemeinschaft (Grant BE 1540/11-1 to K.B.)

They exist in a regulatory gray area, available for research purposes but not sanctioned for medical treatment

doi:10.1371/journal.pone.0199750 67

Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay (Wink et al., 2014, 2017)

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