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5 Conclusions/Outlook Even 200 years after the first description of PD, its pathophysiology is still far from being fully understood

Goud PT, Bai D, Abu-Soud HM (2021) A multiple-hit hypothesis involving reactive oxygen species and myeloperoxidase explains clinical deterioration and fatality in COVID-19

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Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-kappaB signaling and IL-8 expression