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Despite wide dose ranges tested (6 g/kg to 20 mg/kg), multiple administration routes (intramuscular, intraperitoneal, intravenous, oral), and varied dosing frequencies across numerous animal models, no acute lethal dose has been identified

In contrast, Epitalon stimulates the pineal gland to restore natural hormonal balance , offering a more physiological and potentially safer approach to endocrine rejuvenation

doi: 10.1016/j.ijbiomac.2020.12.005 140 KulkarniS

So its not surprising that firms are also researching approaches beyond GLP-1s and amylins

In aged human pinealocytes, Epitalon selectively safeguarded cells from degenerative changes, suggesting a tissue-specific rejuvenating effect on the very gland responsible for circadian control