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Because BDNF activates ARC transcription, ARC expression may also be indirectly downregulated by BDNF-AS

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PMID: 32104332 50

Both NF-B and AP1 induce pro-inflammatory cytokine production, and there is considerable overlap in the target genes activated by these two factors [99,100]

In native endocrine systems, the release of growth hormone from anterior pituitary somatotrophs is regulated by the coordinated, simultaneous actions of endogenous GHRH and ghrelin