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heterophylla , the methanol extract reached 96.67% mortality at 500 ppm, while the aqueous extract rose to 70% at 1000 ppm

however, its clinical use remains limited [50]

Glutathione + Acid Alpha Lipoic (ALA): ALA l cht chng oxy ha c kh nng hot ng c mi trng tan trong nc v tan trong du, ng thi h tr ti to c glutathione v Vitamin C

Toba, et al

3,5-diCQM drives melanogenesis in a dose-dependent manner, and the molecular mechanism underlying its ability to induce pigmentation is through activation of the p38 signaling pathway, phosphorylation and activation of CREB, and a cAMP/PKA dependent signaling pathway, which in turn upregulates the transcription factor MITF, thereby activating tyrosinase activity (Kim et al., 2015)