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On average, a series of 4 to 8 treatments is recommended to achieve the desired results

In a recent article in The Lancet , an international team led by JL Kwiatkowski, F Locatelli and AA Thompson presented their successful multicenter phase 3 clinical trial (HGB-212, NCT03207009) that used gene therapy to treat severe genetic forms of transfusion-dependent -thalassemia

Methods The literature search was carried out using research strings in Pubmed, Scopus, and Mendeley via MeSH, with targeted keywords

The fact that ROS was generated explosively by GSTP-silencing and the incomplete recovery of mitochondrial function by NAC demonstrated in this study indicates that GSTP-silencing induces oxidative stress through mitochondrial dysfunction

Krzystyniak, A [29] and Qu, Y [19] respectively conducted studies on depression using chronic unpredictable stress (CUS) and knockout of Nrf2 as models