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Potential theoretical benefits include: Body composition considerations : Tirzepatide promotes significant fat loss through appetite suppression and metabolic effects, while sermorelin might theoretically support lean muscle preservation through growth hormone stimulationpotentially mitigating the muscle loss sometimes observed with rapid weight reduction

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Both the FDA and the European Medicines Agency are also now considering the approval of semaglutide for the treatment of chronic kidney diseases in patients with type 2 diabetes (Manalac, June 2024