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Attempts to reveal the intra-islet paracrine actions with immunoneutralisation have given conflicting results with both positive effects by retrograde perfusion of the pancreas [6], and no effect on insulin or glucagon secretion [7]

Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy

Nrf2-deficient Female Mice Develop Lupus-like Autoimmune Nephritis

The decision was based on results from the Phase 3 TROPION-Breast02 trial, which enrolled 644 patients and compared the TROP2-directed antibody-drug conjugate against investigators choice of chemotherapy in the first-line setting

Decreased BDNF levels in the hippocampus lead to an increase in the frequency of depressive behaviors, with fluctuations observed throughout the progression of the disease (Martinowich et al., 2007)