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Although the effect of some ER-phagy pathways on sensory neuropathies suggests the importance of this process in the peripheral nervous system, it is difficult to know how important loss of this selective autophagy subtype is for the genesis of neurodegenerative diseases of the central nervous system

iTRAQ-based quantitative proteomic analysis reveals new metabolic pathways responding to chilling stress in maize seedlings

For brain protection, in an animal model of Parkinsons disease, spermidine was shown to dose dependently attenuate striatal pro-inflammatory cytokine levels (TNF-, IL-1, IL-6) and to restore striatal neurochemistry (the level of catecholamines: dopamine, serotonin, nor-epinephrine and their metabolites

[DOI] [PubMed] [Google Scholar] 30.Goldman MP, Gold MH, Palm MD, Coln LE, Preston N, Johnson LA, et al

doi: 10.1038/s41598-022-24039-2