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Description

Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization

24 h) promotes M2 polarization of Raw264.7 macrophages, and drives their repolarization from M1 to M2 via activation of the IL-4/STAT6 and AMPK/SIRT1 signaling pathways [1]

Cell 2020;181:147588

The measured velocities were corrected by subtracting the rate of spontaneous non-enzymatic reaction and three independent experiments were performed at each substrate concentration