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[DOI] [PubMed] [Google Scholar] 81.Luo L., Chen J., Su D., Chen M., Luo B., Pi R., Wang L., Shen W., Wang R

Metformin enhances the antitumor activity of CD8 + T lymphocytes via the AMPK-miR-107-Eomes-PD-1 pathway

it is oil-soluble (unlike L-ascorbic acid) allowing deeper skin penetration before the enzyme activity in skin converts it to active L-ascorbic acid inside the cell