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For oral formulations, morning dosing makes the most practical sense

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Across these trials, tirzepatide delivered dose-dependent improvements in glycemic control and body weight, often surpassing comparators like semaglutide and dulaglutide (43)(44)

Additionally, we are finalizing, with modifications, an amendment to 427.302(e)(4), to use the first month of the first full calendar quarter after the drug is assigned a billing and payment code other than a NOC code as the benchmark period CPI-U for a Part B rebatable drug that was billed under a NOC code during the calendar quarter beginning July 1, 2021, or the third full quarter after such drug's first marketed date, whichever is later