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These findings show that NNMT is involved in regulating the Warburg effect enhancement of chemoresistance and is considered a candidate target for cancer therapy

WGCNA, weighted gene co-expression network analysis

20, 21 Accumulation of ubiquitinated misfolded proteins leads to SQSTM1-mediated activation of NFE2L2

Liu X, Cai Y, Zhang Y, Zhang H, Tian S, Gong Y, Song Q, Chen X, Ma X, Wen Y, et al

Neuroscience 374:271286 Frye RE, Rose S, Slattery J, MacFabe DF (2015) Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome