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The cleaved active SREBP then translocates to the nucleus, binding to SRE promoter regions and activating genes involved in cholesterol, fatty acid, and triglyceride biosynthesisimage created by BioRender

R 5 is selected from the group consisting of: hydrogen, CH2-O-CO-Y, and ^ CH(R a )-0- each R 6 is independently selected from the group consisting of: hydrogen, deuterium, wherein optionally Z and W are taken together to form a C3-C8 heterocycloalkyl or C 4 - C10 heteroaryl or fused bicyclic ring system in which one of the rings is a C4-C10 heteroaryl

This study showed that the sows' serum content of LDL had tended to increase and the piglets' serum content of ALT, CHOL, and LDL significantly increased in the CAT group, which demonstrated that maternal CAT supplementation had an effect in regulating blood lipid

A key role for NF-B transcription factor c-Rel in T-lymphocyte-differentiation and effector functions