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That cyclopropane lipids may act as specific signaling molecules in humans is suggested by in vitro assays in which cyclopropane fatty acids, but not simple saturated fatty acids, activated the G-protein coupled receptors brain angiogenesis factor 1 (BAI1) 80 and G-protein coupled receptor 84 (GPR84) 81

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Since the introduction of the laparoscopic technique to PEH treatment by Cuschieri [14] in 1992, the minimally invasive approach has spread rapidly

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