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The studies were short, involved small numbers and often provided limited information about safety monitoring

The combined signaling creates thermogenic effects that neither GLP-1 nor GIP activation produces on its own

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Asthmas complex heterogeneity has led to the identification of distinct asthma clusters, or endotypes, that are defined by their shared clinical features, or phenotypes, shown in Fig

UK patients should understand that: Available evidence is largely from Phase 2 studies with relatively short follow-up periods Long-term cardiovascular outcome data are not yet available for either agent Phase 3 trials are ongoing, and results will inform future regulatory submissions to the MHRA UK patients interested in accessing these treatments through clinical trials may wish to consult the NIHR 'Be Part of Research' portal (bepartofresearch.nihr.ac.uk) or ClinicalTrials.gov for current recruitment opportunities