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Transposition of BDNF to the target injury regions is a challenge in clinical applications, while a short half-life and a low rate of transport through the blood-brain barrier (BBB) is hampered

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NAD + metabolism in neurodegenerative disorders Neurodegenerative diseases are a heterogeneous group of diseases, including Alzheimers disease (AD), Parkinsons disease (PD) and amyotrophic lateral sclerosis (ALS), which are characterized by progressive degeneration of the structure and function of the peripheral and central nervous system, with the characteristics like the accumulation of misfolded and aggregated proteins that are associated with severe proteotoxic stress (Fig

Chromosomes, which are responsible for our genetic makeup, have telomeres on their ends, which shorten each time that cell division takes place