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The Nutrient Reference Value (NRV) for adults aged 19-64 is 2.5mcg a day

Although current evidence strongly supports its dynamic involvement in disease development, it remains uncertain whether OS acts primarily as an initiating factor, an amplifying mechanism, or a downstream consequence of placental dysfunction 27

Modulation of the gene expression of annulus fibrosus-derived stem cells using poly(ether carbonate urethane)urea scaffolds of tunable elasticity

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For this reason, smaller organoid systems may be preferred at the expense of low cellular diversity, loss of long-range connectivity, and electrophysiological properties that do not fully recapitulate disease states [225, 226]