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Laurent, C

As the condition worsens, such as in decompensated liver cirrhosis, microbiota dysbiosis is maintained and further exacerbated 78,79

TB-500 operates primarily through actin dynamics: it binds G-actin monomers to regulate the monomeric actin pool, which is thought to influence cell migration in experimental wound models

Furthermore, as trauma is undoubtedly at the origin of PD and even micro-injuries may bear serious consequences in genetically predisposed patients, even injections must be considered a source of microtrauma for the tissues, therefore we made sure to use a very thin needle when performing the injections in the area around the plaque, and we decreased the number of injections at every treatment cycle