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These compounds have several biological functions, including growth-promoting and immunostimulant activities (Hoseinifar et al., 2011)

In Caenorhabditis elegans , IL-17 has been shown to directly bind to its receptor on neurons to increase synaptic activity and modulate behavior [118]

Conversely, under conditions of iron deficiency or cellular stress, NCOA4 levels increase to promote ferritin degradation and maintain essential iron supply for metabolic processes (81,87,88)

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PARK2 knockout mice exposed to rotenone had a significantly higher relative abundance of Firmicutes , Cyanobacteria , and significantly lower abundance of Bacteroidetes , and Verrucomicrobia compared to non-rotenone-exposed PARK2 mice (Supplementary Table 5)