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In contrast, Th2 cells are induced by IL-4, which promotes the expression of GATA-binding protein 3 (GATA3) and leads to the production of IL-4, IL-5, and IL-13, all of which play key roles in driving allergic inflammation (Ruterbusch et al., 2020)

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Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study

Johnstone RW, See RH, Sells SF, Wang J, Muthukkumar S, Englert C, Haber DA, Licht JD , Sugrue SP, Roberts T, Rangnekar VM, Shi Y

If response plateaus or visceral fat does not move, the clinic catches that early instead of three cycles later