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However, in metabolic diseases like obesity, reduced SCFA levels impair GPR43-mediated insulin sensitivity, whereas to their protective role in IBD via inflammasome activation

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The international community has proposed the terms metabolic dysfunction-associated steatotic liver disease (MASLD) and its inflammatory subtype, metabolic dysfunction-associated steatohepatitis (MASH), as updated designations intended to encompass the disease spectrum previously described by non-alcoholic fatty liver disease (NAFLD) and, in part, metabolic-associated fatty liver disease (MAFLD)

Moniz T, Lima S A C, Reis S

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