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As discussed, future research should focus on the design and functionalization of novel nanomaterials with enhanced targeting specificity for different retinal cell types or disease stages, the development of multifunctional NPs that combine drug delivery with diagnostic capabilities (theranostics), the development of responsive NPs that can release their drug payload in response to specific stimuli (such as light, temperature, pH, or specific biomarkers), and the exploration of novel NPs that possess inherent therapeutic properties (Table 12)

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DOI: 10.1016/0041-008x(84)90279-5 40